Biochemistry

Q1/A/ Choose  the correct answer                                          ( 12 Mark)

1-Glucose-6-phosphatase is absent or deficient in:

(A) Von Gierke’s disease

(B) Pompe’s disease

(C) Cori’s disease

)D) McArdle’s disease

2- Glycogenin is

)A) Uncoupler of oxidative phosphorylation

)B) Polymer of glycogen molecules

)C) Protein primer for glycogen synthesis

)D) Intermediate in glycogen breakdown

3-The conversion of alanine to glucose is termed:

)A) Glycolysis

)B) Oxidative decarboxylation

)C) Specific dynamic action

)D) Gluconeogenesis

4-Conversion of glucose to glucose-6-phosphate in human liver is by

)A) Hexokinase only

)B) Glucokinase only

)C) Hexokinase and glucokinase

)D) Glucose-6-phosphate dehydrogenase

 

5-A fatty acid which is not synthesized in the body and has to be supplied in the diet is

)A) Palmitic acid (B) Lauric acid

)C) Linolenic acid (D) Palmitoleic acid

6-Net energy generation on complete oxidation of linoleic acid by old calculation is:

)A) 148 ATP equivalents

)B) 146 ATP equivalents

)C) 144 ATP equivalents

)D) 143 ATP equivalents

Q1/B/ Answer the following questions:                                   ( 8 Marks)

1- Which pathway can provide the energy for the muscles in absence of oxygen.

2- Mention the amino acid(s) that cannot be converted to glucose.

3-   Give the effects of insulin on the main carbohydrates pathways.

4-   Mention the rate limiting step of fatty acid breakdown

 

 

Q1/A/  Choose the correct answer.                                        (12 Mark)

  

A)  = 0

B)   = 1

C)  = 2

D)  = 3

2-Which of the following is (R)-3-hexanol?

 

3-Which of the following compounds is cyclopentyldiethylamine?

 

 

4- What is the chief product from the following reaction? 

5- Which of the following compounds is the strongest base? 

A)  (CH3)2NCH2CO2CH3

B)   (CH3)2NCOCH3

C)  (CH3)2NC≡N

D)  (CH3)2N-N=O

6- Which of the following may be classified as an acetal? 

 

A)  I & II

B)   III & IV

C)   Only IV

D)  All but IV

Q/2/ B/ 1- The IUPAC name for (C₂H₅)₂C=C(CH₃)CH₂CO₂H is ... ?

(8 Marks)

2- Give the two examples  of the nucleophilic substitution reactions of carboxylic acid derivatives ?

3- Give the number of isomers of 1,2-dibromocyclohexane ?

4- Give the 1HNMR spectra of p-Ethoxybenzaldehyde ?

 

 

 

Inorganic Chemistry

Q5/A/ Choose the right answer                                               (12 Mark)

1- The maximum value of crystal field stabilization energy in the complex :

A) [Co(Cl)₆]

B)K₃[Co(CN)₆]

C)K₃[Co(Cl)₆]

D)Cl₂[Co(NH₃)₆]

 2-It is expected The magnetic susceptibility of the complexes Na₃ [Fe(CN)₆]:

A)  2.8B.M.

B)   4.8B.M.

C)   1.9B.M.

D)  3.8B.M.

3- (Crystal Field Theory) When the valence d orbitals of the central metal ion are split in energy in an octahedral ligand field, which orbitals are raised least in energy?

A) d_xy and d_x2_-y2

B) d_xy, d_xz and d_yz

C) d_xz and d_yz

D) d_xz, d_yz and d_z2

4- which of the complex is more stable :

A)[Co(NH₃)₆]²⁺

B) [Co(NH₃)₆]³⁺ ,

C)[Co(en)₃]²⁺,

D)[Co(en)₃]³⁺,

5- which of the following will not give test for chloride ions with silver nitrate at 25 ⁰C

A)CoCl₃.3NH₃

B)CoCl₃.4NH₃

C)CoCl₃.5NH₃

D)CoCl₃.6NH₃

6- according to the Orgel diagram the complex [Co(NH₃)₆]²⁺ exhibited the transitions :

A) ³A_2g → ³T_2g(F)←, ³A_2g→³T_1g(F) , ³A_2g→³T_1g(P)

B) ³A_2g → ³T_2g(F), ³A_2g→³T_1g(F) , ²A_2g→²T_1g(P)

C) ³A_2g → ³T_2g(p), ³A_2g→³T_1g(F) , ³A_2g→³T_1g(P)

D) none of these

Q5/B/ 1-For spin-orbit coupling to occur, following three conditions must be satisfied by :                                                           ( 8 Marks)                                                                                                       

2- Comparism between Valence bond (VB) Theory, Crystal Field Theory (CFT).